(3-Bromo-4-chlorophenyl)methanol → 3-Bromo-4-chlorobenzaldehyde

HRID 460126

反応式

HRID 460126 の反応式
[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH2:5][OH:6]>CC(C)=O.O=[Mn]=O>[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH:5]=[O:6]

参加物

4

反応物 1

HCID 50998689(3-Bromo-4-chlorophenyl)methanol

生成物 1

HCID 140498093-Bromo-4-chlorobenzaldehyde収率 62.4%

試薬・触媒・溶媒 2

HCID 14801Manganese dioxide触媒HCID 180Acetone溶媒

実験手順

A solution of 3-bromo-4-chlorobenzyl alcohol (3.24 g, 14.6 mmol) in acetone (100 mL) was treated with MnO2 (16.2 g, 73 mmol) and the mixture stirred for 3 days then filtered over diatomaceous earth. The filtrate was concentrated under reduced pressure to afford 2.0 g of title compound.

後処理

  1. filtrationthen filtered over diatomaceous earth
  2. concentrationThe filtrate was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-294ab56614fc44a6a54189571da03d8a
出典データセット
uspto-grants-2007_03
特許番号
US07196102B2

関連ノート

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