Acetic acid 3-benzyloxycarbonylamino-4-oxo-azetidin-2-yl ester → Acetic acid 3-amino-4-oxo-azetidin-2-yl ester
反応式
C(OC([NH:11][CH:12]1[C:15](=[O:16])[NH:14][CH:13]1[O:17][C:18](=[O:20])[CH3:19])=O)C1C=CC=CC=1>[Pd].C(OCC)(=O)C>[NH2:11][CH:12]1[C:15](=[O:16])[NH:14][CH:13]1[O:17][C:18](=[O:20])[CH3:19]参加物
4
実験手順
Acetic acid 3-benzyloxycarbonylamino-4-oxo-azetidin-2-yl ester (100 mg, 0.36 mmol) was hydrogenated on a Parr shaker over 10% palladium on carbon (100 mg) in ethyl acetate (20 ml) at 50 psi for 5 h. The mixture was filtered through Celite and evaporated. Acetic acid 3-amino-4-oxo-azetidin-2-yl ester was obtained in quantitative yield.
後処理
- filtrationThe mixture was filtered through Celite
- customevaporated
出典と根拠
- ORDレコード
- ord-3cfe61c790c5448d851567369623ad4d
- 出典データセット
- uspto-grants-2007_03
- 特許番号
- US07196099B2
反応ノート
読み込み中…