p-Toluenesulfonic acid → HCID 20367180、化合物
反応式
[CH3:1][C:2]1[CH:10]=[CH:9][C:8]([CH3:11])=[CH:7][C:3]=1[CH2:4][NH:5][NH2:6].C([O:14][C:15](=O)[CH:16]=[C:17]([NH2:21])OCC)C.C1(C)C=CC(S(O)(=O)=O)=CC=1>C(O)C>[NH2:21][C:17]1[NH:6][N:5]([CH2:4][C:3]2[CH:7]=[C:8]([CH3:11])[CH:9]=[CH:10][C:2]=2[CH3:1])[C:15](=[O:14])[CH:16]=1参加物
5
実験手順
26.6 g of 2,5-dimethylbenzylhydrazine were added dropwise to a solution of 28.2 g of β-amino-β-ethoxyacrylic acid ethyl ester and 1 g of p-toluenesulphonic acid in 130 ml of ethanol, in the course of which the temperature rose from 25° to 35° C. After stirring overnight, the compound identified above separated out, and was filtered off and recrystallised from ethanol. Melting point: 124°, 20 g (52%).
後処理
- customrose from 25° to 35° C
- customabove separated out
- filtrationwas filtered off
- customrecrystallised from ethanol
出典と根拠
- ORDレコード
- ord-62c0232e3fd646248b6d2c5a81db372f
- 出典データセット
- uspto-grants-1977_12
- 特許番号
- US04061653
反応ノート
読み込み中…