p-Toluenesulfonic acid → HCID 20367322、化合物
反応式
C([O:3][C:4](=O)[CH:5]=[C:6]([NH2:10])OCC)C.C1(C)C=CC(S(O)(=O)=O)=CC=1.[Br:23][C:24]1[CH:25]=[C:26]([CH:30]=[CH:31][CH:32]=1)[CH2:27][NH:28][NH2:29]>C(O)C>[NH2:10][C:6]1[NH:29][N:28]([CH2:27][C:26]2[CH:30]=[CH:31][CH:32]=[C:24]([Br:23])[CH:25]=2)[C:4](=[O:3])[CH:5]=1参加物
5
実験手順
20.5 g of β-amino-β-ethoxyacrylic acid ethyl ester together with 1.5 g of p-toluenesulphonic acid were dissolved in 200 ml of ethanol. 26 g of m-bromobenzylhydrazine were added dropwise to this solution, under nitrogen. After stirring for two hours, the mixture was left to stand overnight and the compound identified above, which had separated out as a precipitate, was filtered off and recrystallised from ethanol. Melting Point: 160°, 12 g (35%).
後処理
- waitthe mixture was left
- waitto stand overnight
- customhad separated out as a precipitate
- filtrationwas filtered off
- customrecrystallised from ethanol
出典と根拠
- ORDレコード
- ord-2bee44edf3834bf3a5f2005a4d656082
- 出典データセット
- uspto-grants-1977_12
- 特許番号
- US04061653
反応ノート
読み込み中…