N,N'-Diethylthiourea → 3-Ethyl-2-ethylimino-4-(4-bromo-3-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrochloride

HRID 461152

反応式

HRID 461152 の反応式
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:11])[CH2:9][Cl:10])=[CH:4][C:3]=1[S:12](=[O:15])(=[O:14])[NH2:13].[CH2:16]([NH:18][C:19]([NH:21][CH2:22][CH3:23])=[S:20])[CH3:17]>>[ClH:10].[CH2:22]([N:21]1[C:8]([C:5]2[CH:6]=[CH:7][C:2]([Br:1])=[C:3]([S:12](=[O:15])(=[O:14])[NH2:13])[CH:4]=2)([OH:11])[CH2:9][S:20][C:19]1=[N:18][CH2:16][CH3:17])[CH3:23]

参加物

3

反応物 2

HCID 2735009N,N'-DiethylthioureaHCID 227606054'-Bromo-3'-sulfamoyl-2-chloroacetophenone

生成物 1

HCID 227605693-Ethyl-2-ethylimino-4-(4-bromo-3-sulfamoylphenyl)-1,3-thiazolidine-4-ol-hydrochloride

実験手順

4.6 g of 4'-bromo-3'-sulfamoyl-2-chloroacetophenone and 1.8 g of ground 1,3-diethylthiourea were reacted and worked up according to the prescription given in Example 12. Colorless solid body, decomposition beginning at 103° C, C=N 1615 cm-1.

後処理

  1. customat 103° C

出典と根拠

ORDレコード
ord-81597a29f4e242539630fe9460ef98a4
出典データセット
uspto-grants-1977_12
特許番号
US04061761

関連ノート

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