Cyclooctylamine → HCID 22760619、化合物

反応式

[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[S:11](Cl)(=[O:13])=[O:12].[CH:15]1([NH2:23])[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1>>[Cl:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[S:11](=[O:13])(=[O:12])[NH:23][CH:15]1[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1

参加物

反応物 2

HCID 2903Cyclooctylamine

HCID 756134-Chloro-3-(chlorosulphonyl)benzoic acid

生成物 1

HCID 22760619HCID 22760619、化合物

実験手順

25.5 g of 4-chloro-3-chlorosulfonylbenzoic acid were reacted as prescribed in Example 75a) with 45 g of cyclooctyl amine and worked up. The crystallized 4-chloro-3-cyclooctylsulfamoylbenzoic acid so obtained was dried end reacted without further purification in thionyl chloride as prescribed in Example 74a). Colorless crystals, melting point: 134° C.

出典と根拠

ORDレコード: ord-1ee46a34aef149b2b188c345e9d69f04
出典データセット: uspto-grants-1977_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04061761

反応ノート

読み込み中…