Benzoyl Peroxide → alpha-Bromo-2-chloro-m-tolyl 2-thienyl ketone
反応式
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([C:8]1[C:9]([Cl:15])=[C:10]([CH3:14])[CH:11]=[CH:12][CH:13]=1)=[O:7].[Br:16]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([C:8]1[C:9]([Cl:15])=[C:10]([CH2:14][Br:16])[CH:11]=[CH:12][CH:13]=1)=[O:7]参加物
5
実験手順
A mixture of 11.8 parts of 2-chloro-m-tolyl 2-thienyl ketone, 8.9 parts of N-bromosuccinimide, 100 parts of carbon tetrachloride and 0.25 parts of benzoyl peroxide is stirred and refluxed for 2 hours. The precipitated succinimide is filtered off and washed on the filter with carbon tetrachloride. The filtrate is dried and evaporated, yielding α-bromo-2-chloro-m-tolyl 2-thienyl ketone as a residue.
後処理
- temperaturerefluxed for 2 hours
- filtrationThe precipitated succinimide is filtered off
- washwashed on the
- filtrationfilter with carbon tetrachloride
- customThe filtrate is dried
- customevaporated
出典と根拠
- ORDレコード
- ord-5bb4374b95d04416ae0188d68334a763
- 出典データセット
- uspto-grants-1977_12
- 特許番号
- US04064132
反応ノート
読み込み中…