Acetone → 3-Azidosulfonylbenzoic acid

HRID 462142ノート

反応式

HRID 462142 の反応式
[N-:1]=[N+:2]=[N-:3].[Na+].Cl[S:6]([C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][CH:17]=1)[C:12]([OH:14])=[O:13])(=[O:8])=[O:7].CC(C)=O>O>[N:1]([S:6]([C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][CH:17]=1)[C:12]([OH:14])=[O:13])(=[O:8])=[O:7])=[N+:2]=[N-:3]

参加物

5

反応物 3

HCID 180AcetoneHCID 33557Sodium AzideHCID 77641Benzoic acid, 3-(chlorosulfonyl)-

生成物 1

HCID 28289923-Azidosulfonylbenzoic acid

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

In a three-necked flask fitted with stirrer and dropping funnel 65 g of sodium azide is dissolved in 900 ccs of water. While stirring and cooling till 0°-5° C a solution of 198 g of m-chlorosulphonyl-benzoic acid in 900 ccs of acetone is added dropwise. Then stirring is continued for 30 minutes whereupon the solution obtained is poured into 2 liters of water. The white precipitate formed is sucked off, washed with water and dried in vacuo. Melting point: 143° C.

後処理

  1. customIn a three-necked flask fitted with stirrer
  2. additionis added dropwise
  3. stirringThen stirring
  4. customobtained
  5. customThe white precipitate formed
  6. washwashed with water
  7. customdried in vacuo

出典と根拠

ORDレコード
ord-adb3c8dce7e84e30a229d286fcefd46d
出典データセット
uspto-grants-1977_12
特許番号
US04065524

反応ノート

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