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Piperazine → 2-[2-(1-Piperazinyl)-5-thiadiazolyl]-1-methyl-5-nitroimidazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Piperazine | HCID 4837 | — |
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | 2-(2-Piperidino-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390837 | — |
| 生成物 | 2-[2-(1-Piperazinyl)-5-thiadiazolyl]-1-methyl-5-nitroimidazole | HCID 21390830 | — |
反応手順
The preparation of the subject compound is carried out essentially as described for the 2-piperidino derivative (Example 28), two equivalents of piperazine replacing the piperidine. The crude project is recrystallized from 2-methoxyethanol to yield the pure compound melting at 240°-241° C. ;cl EXAMPLE 24
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04065567 |
| 出典データセット | uspto-grants-1977_12 |
| ORD ID | ord-12914646f91d4db4b530caf5515c91e9 |
| 出典メモ | uspto-grants-1977_12 |