Hydrochloric Acid → HCID 20398034、化合物

HRID 462392ノート

反応式

HRID 462392 の反応式
C[O:2][C:3](=[O:22])[CH2:4][CH2:5][CH:6]=[C:7]=[CH:8][CH2:9][S:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21].O.[OH-].[Li+].Cl>C(O)C>[C:3]([OH:22])(=[O:2])[CH2:4][CH2:5][CH:6]=[C:7]=[CH:8][CH2:9][S:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH3:21]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 962WaterHCID 3939Lithium HydroxideHCID 20397918HCID 20397918、化合物

生成物 1

HCID 20398034HCID 20398034、化合物収率 59.7%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

Methyl-8-thianonadeca-4,5-dienoate (210 mg) was treated in 10 ml of ethanol and 1 ml of water with 160 mg of lithium hydroxide at room temperature for 18 hours. The solution was acidified to pH 4 with dilute HCl and extracted with diethyl ether twice. The ethereal extracts were washed with brine and dried over potassium carbonate to give 120 mg of 8-thianonadeca-4,5-dienoic acid. This procedure can be used to convert the compounds of Example VI to their corresponding acid.

後処理

  1. extractionextracted with diethyl ether twice
  2. washThe ethereal extracts were washed with brine
  3. dry with materialdried over potassium carbonate

出典と根拠

ORDレコード
ord-671f7947c6a8469d886ab0ab0a9f6fc3
出典データセット
uspto-grants-1985_05
特許番号
US04515727

反応ノート

読み込み中…