Methane → 2-(Dimethoxymethyl)-6-hydroxy-2,5,7,8-tetramethyl-chroman
反応式
[CH3:1][O:2][CH:3]([O:19][CH3:20])[C:4]1([CH3:18])[CH:13]=[CH:12][C:11]2[C:6](=[C:7]([CH3:17])[C:8]([CH3:16])=[C:9]([OH:15])[C:10]=2[CH3:14])[O:5]1.C>CO.[Pd]>[CH3:20][O:19][CH:3]([O:2][CH3:1])[C:4]1([CH3:18])[CH2:13][CH2:12][C:11]2[C:6](=[C:7]([CH3:17])[C:8]([CH3:16])=[C:9]([OH:15])[C:10]=2[CH3:14])[O:5]1参加物
5
実験手順
1.74 g (0.63 mmole) of the chromene obtained in Example 7 were hydrogenated in 30 ml of methanol at room temperature and under atmospheric pressure using 0.15 g of a supported catalyst comprising 10% by weight of Pd on active charcoal, in the course of 16 hours. Conventional working up gave the above compound, in 97% yield, as white crystals of melting point 102°-106° C.
後処理
- customin the course of 16 hours
- customConventional working up gave the above compound
出典と根拠
- ORDレコード
- ord-ca3428634f6d4924ad011f34d161f89b
- 出典データセット
- uspto-grants-1985_05
- 特許番号
- US04515975
反応ノート
読み込み中…