Acetic Acid → Acetanilide

HRID 46430

反応式

HRID 46430 の反応式
[PH4+].[C:2]([OH:5])(=O)[CH3:3].[NH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[C:2]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)(=[O:5])[CH3:3]

参加物

4

反応物 3

HCID 176Acetic AcidHCID 6115AnilineHCID 5460504Phosphonium

生成物 1

HCID 904Acetanilide収率 20%

実験手順

To the same reaction mixture containing the phosphonium salt as in Example 1 was added a mixture of 3.0 g. (0.05 mole) of acetic acid and 5.2 g. (0.056 mole) of aniline, and the resulting mixture was reacted under reflux for 2 hours. Thereafter, the same aftertreatment as in Example 1 was effected to obtain acetanilide, yield 20% based on acetic acid.

後処理

  1. additionwas added
  2. additiona mixture of 3.0 g
  3. temperatureunder reflux for 2 hours

出典と根拠

ORDレコード
ord-5125bfbe373845828fb7c1f366821596
出典データセット
uspto-grants-1979_11
特許番号
US04173563

関連ノート

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