Thiophenol → N-benzyloxycarbonyl-glycine-phenythio ester

HRID 46434

反応式

HRID 46434 の反応式
[C:1]1([SH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH:8]([C:13]([O:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1)=[O:14])[CH2:9][C:10]([OH:12])=[O:11]>ClCCl>[C:1]1([S:7][O:12][C:10](=[O:11])[CH2:9][NH:8][C:13]([O:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:14])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

参加物

4

反応物 2

HCID 7969ThiophenolHCID 14349Benzyloxycarbonylglycine

生成物 1

HCID 22764889N-benzyloxycarbonyl-glycine-phenythio ester収率 62%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

Using thiophenol and Z-Gly.OH, Example 78 was repeated; except that dichloromethane was used in place of ethyl acetate as the extraction solvent, to obtain N-benzyloxycarbonyl-glycine-phenythio ester (hereinafter represented by ##STR12## in a yield of 62%.

出典と根拠

ORDレコード
ord-01bd8ea14e7b4957854705e522f04f34
出典データセット
uspto-grants-1979_11
特許番号
US04173563

関連ノート

読み込み中…