1,3,5-Trifluorobenzene → 1,3,5-Trifluoro-2,4-dinitrobenzene

HRID 46460

反応式

HRID 46460 の反応式
FC1C=C(F)C=C(F)C=1.[N+]([O-])([O-])=O.[K+].[F:15][C:16]1[C:21]([N+:22]([O-:24])=[O:23])=[C:20]([F:25])[C:19]([N+:26]([O-:28])=[O:27])=[C:18]([F:29])[C:17]=1[N+:30]([O-:32])=[O:31]>>[F:15][C:16]1[CH:21]=[C:20]([F:25])[C:19]([N+:26]([O-:28])=[O:27])=[C:18]([F:29])[C:17]=1[N+:30]([O-:32])=[O:31].[F:15][C:16]1[C:21]([N+:22]([O-:24])=[O:23])=[C:20]([F:25])[C:19]([N+:26]([O-:28])=[O:27])=[C:18]([F:29])[C:17]=1[N+:30]([O-:32])=[O:31]

参加物

5

反応物 3

HCID 97451,3,5-Trifluorobenzene2 回HCID 24434Potassium Nitrate2 回HCID 10706903HCID 10706903、化合物

生成物 2

HCID 2230761,3,5-Trifluoro-2,4-dinitrobenzeneHCID 10706903HCID 10706903、化合物

実験手順

The temperature must be carefully controlled during this process. During the addition of 1,3,5-trifluorobenzene, the potassium nitrate-fuming sulfuric acid mixture must be kept at a temperature in the range of from about 30° C. to about 50° C. The temperature is controlled by regulating the rate at which 1,3,5-trifluorobenzene is added to the potassium nitrate-fuming sulfuric acid mixture and also through external cooling of the reaction mixture. After the initial exothermic reaction is over, the reaction mixture is heated into the range of from about 140° C. to about 160° C. but preferably from 150° C. to 156° C. where it is maintained until the optimum or desired yield of 1,3,5-trifluoro-2,4,6-trinitrobenzene is obtained. If the reaction temperature is too high, the yield will be reduced through the decomposition of the product. On the other hand, if the reaction temperature is too low, 1,3,5-trifluoro-2,4-dinitrobenzene will be produced at the expense of the 1,3,5-trifluoro-2,4,6-trinitrobenzene.

後処理

  1. custommust be kept at a temperature in the range of from about 30° C. to about 50° C
  2. temperaturealso through external cooling of the reaction mixture
  3. customAfter the initial exothermic reaction
  4. temperatureis heated into the range of from about 140° C. to about 160° C. but preferably from 150° C. to 156° C. where it
  5. temperatureis maintained until the optimum
  6. customis obtained
  7. customthe yield will

出典と根拠

ORDレコード
ord-b2a4b6352dc0404dac9973aca4a28c6f
出典データセット
uspto-grants-1979_11
特許番号
US04173591

関連ノート

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