化工社化工社 化学情報印刷レポート · 研究参考用
Hydrochloric Acid → Ethyl beta-amino-beta-ethoxyacrylate hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Ethyl cyanoacetate | HCID 7764 | — |
| 反応物 | tert-Butyl methyl ether | HCID 15413 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | Ethyl beta-amino-beta-ethoxyacrylate hydrochloride | HCID 53395434 | — |
反応手順
A solution of 226 g of ethyl cyanoacetate in 200 ml of absolute ethanol is saturated by introducing hydrochloric acid gas at 0°. The mixture is stirred at 0° overnight and then 1.5 l of tert.butyl methyl ether are added thereto. The ethyl β-amino-β-ethoxyacrylate hydrochloride which thereby precipitates is filtered off under suction, washed portionwise with 0.5 l of tert.butyl methyl ether and dried at 35° in vacuo. There is obtained ethyl β-amino-β-ethoxyacrylate hydrochloride, melting point 103°-104°.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04549019 |
| 出典データセット | uspto-grants-1985_10 |
| ORD ID | ord-e155882b0fa7469fa0377d662f9667dc |
| 出典メモ | uspto-grants-1985_10 |