N-(4-nitrophenyl)pentanamide → N-(4-aminophenyl)pentanamide

HRID 46497ノート

反応式

HRID 46497 の反応式
[N+:1]([C:4]1[CH:16]=[CH:15][C:7]([NH:8][C:9](=[O:14])[CH2:10][CH2:11][CH2:12][CH3:13])=[CH:6][CH:5]=1)([O-])=O>C(O)C.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([NH:8][C:9](=[O:14])[CH2:10][CH2:11][CH2:12][CH3:13])=[CH:15][CH:16]=1

参加物

4

反応物 1

HCID 3762929N-(4-nitrophenyl)pentanamide

生成物 1

HCID 1725711N-(4-aminophenyl)pentanamide

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

A solution of 4'-nitrovaleranilide (13.33 g., 0.06 mole) in absolute ethanol (750 ml.) is hydrogenated over 10% palladium on charcoal (2 g.) until the theoretical absorption is achieved. The catalyst is removed and the solvent is removed in vacuo. The residue is recrystallized from butyl chloride to yield 9.0 g., m.p. 81°-83° C.

後処理

  1. customThe catalyst is removed
  2. customthe solvent is removed in vacuo
  3. customThe residue is recrystallized from butyl chloride
  4. customto yield 9.0 g

出典と根拠

ORDレコード
ord-3396c84eaf1e4e19806d6ff0038281c7
出典データセット
uspto-grants-1979_11
特許番号
US04173646

反応ノート

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