Acetone → HCID 20261919、化合物

HRID 465105

反応式

HRID 465105 の反応式
[C:1]1([CH:7]2[CH2:14][N:13]3[C:9]([S:10][CH2:11][CH2:12]3)=[N:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:15][CH2:16][C:17]([OH:19])=[O:18].[CH3:20]C(C)=O>>[Br-:15].[C:1]1([CH:7]2[CH2:14][N+:13]3[CH2:12][CH2:11][S:10][C:9]=3[N:8]2[CH2:16][C:17]([O:19][CH3:20])=[O:18])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

参加物

4

反応物 3

HCID 180AcetoneHCID 3913(+-)-TetramisoleHCID 6227Bromoacetic Acid

生成物 1

HCID 20261919HCID 20261919、化合物収率 81%

実験手順

2 g (0.01 mol) of 2,3,5,6-tetrahydro-6-phenylimidazo-[2,1-b]-thiazole are dissolved in 20 ml of acetone and added with 1.53 g (0.01 mol) of methyl ester of monobromacetic acid. After 12 hours the residue is filtered-off and washed with acetone to give 2.86 g (81%) of 2,3,5,6-tetrahydro-6-phenyl-7-methoxycarbonylmethylimidazo-[2,1-b]-thiazolium bromide melting at 81°-82° C. (from dioxane).

後処理

  1. washwashed with acetone

出典と根拠

ORDレコード
ord-282bffce6faf4ef09327d9ede0c4e36e
出典データセット
uspto-grants-1985_10
特許番号
US04550170

関連ノート

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