Hydrazine → 2-Hydrazino-3,3'-bipyridine

HRID 465131ノート

反応式

HRID 465131 の反応式
Br[C:2]1[C:7]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:6][CH:5]=[CH:4][N:3]=1.[NH2:14][NH2:15]>N1C=CC=CC=1>[NH:14]([C:2]1[C:7]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:6][CH:5]=[CH:4][N:3]=1)[NH2:15]

参加物

4

反応物 2

HCID 9321HydrazineHCID 135337192-Bromo-3,3'-bipyridine

生成物 1

HCID 135337152-Hydrazino-3,3'-bipyridine

試薬・触媒・溶媒 1

HCID 1049Pyridine溶媒

反応条件

温度
100 °C

実験手順

A mixture of 16.46 g of 2'-bromo-3,3'-bipyridine, 24 ml of anhydrous hydrazine and 500 ml of dry pyridine was heated at 100° C. for 3 days. The solvent was removed under vacuum, toluene was added and removed and the residue was partitioned between saturated aqueous sodium carbonate and methylene chloride. The organic layer was dried, the solvent removed under vacuum and the residue crystallized from methylene chloride-hexane, giving 2'-hydrazino-3,3'-bipyridine as tan crystals.

後処理

  1. customThe solvent was removed under vacuum, toluene
  2. additionwas added
  3. customremoved
  4. customthe residue was partitioned between saturated aqueous sodium carbonate and methylene chloride
  5. customThe organic layer was dried
  6. customthe solvent removed under vacuum
  7. customthe residue crystallized from methylene chloride-hexane

出典と根拠

ORDレコード
ord-be94748dd56543058014dafbf39d5368
出典データセット
uspto-grants-1985_10
特許番号
US04550166

反応ノート

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