Dimethylformamide → n-Octyl 1-benzotriazolyl ether

HRID 46588

反応式

HRID 46588 の反応式
[OH:1][N:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[N:4]=[N:3]1.CN(C)C=O.Cl[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24].C(=O)([O-])[O-].[K+].[K+]>O>[N:2]1([O:1][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH3:24])[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[N:4]=[N:3]1

参加物

6

反応物 4

HCID 6228DimethylformamideHCID 81421-ChlorooctaneHCID 11430Potassium CarbonateHCID 757711-Hydroxybenzotriazole

生成物 1

HCID 12702944n-Octyl 1-benzotriazolyl ether

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
135 °C

実験手順

A mixture of 1-hydroxybenzotriazole (30.6 g), N,N-dimethylformamide (150 ml), 1-chlorooctane (32.7 g) and potassium carbonate (50 g) was heated at 135° C. for 0.5 hr. while stirring. The reaction mixture was poured into water and the resulting mixture was extracted with benzene. The benzene extract was dried and stripped of solvent by rotary evaporation and distillation to a pot temperature of 100 C. at a pressure of less than 0.1 mm of mercury. The product, n-octyl 1-benzotriazolyl ether was obtained as a clear yellow oil residue. The elemental analysis was as follows:

後処理

  1. extractionthe resulting mixture was extracted with benzene
  2. extractionThe benzene extract
  3. customwas dried
  4. customstripped of solvent by rotary evaporation and distillation to a pot temperature of 100 C

出典と根拠

ORDレコード
ord-26af1a8e5e894fab9e9eb7ac561c0fff
出典データセット
uspto-grants-1979_11
特許番号
US04174285

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