1-Amino 2-nitro-4-(2,2-dichloro-1-methylethenyl) benzene → 1,2-Diamino-4-(2,2-dichloro-1-methylethenyl) benzene

HRID 46622ノート

反応式

HRID 46622 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:12])=[C:9]([Cl:11])[Cl:10])=[CH:4][C:3]=1[N+:13]([O-])=O>[Fe].C(O)C>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:12])=[C:9]([Cl:10])[Cl:11])=[CH:4][C:3]=1[NH2:13]

参加物

4

反応物 1

HCID 213924321-Amino 2-nitro-4-(2,2-dichloro-1-methylethenyl) benzene

生成物 1

HCID 545190211,2-Diamino-4-(2,2-dichloro-1-methylethenyl) benzene

試薬・触媒・溶媒 2

HCID 23925Iron触媒HCID 702Ethanol溶媒

実験手順

A mixture of 2.1 g. (8.5 mmoles) of 1-amino 2-nitro-4-(2,2-dichloro-1-methylethenyl) benzene 2.1 g. (0.038 moles) of iron powder is suspended in 80 ml. of 40% ethanol and refluxed for 30 minutes. The reaction mixture is filtered while hot, the solid material washed with ethanol and extracted with chloroform and evaporated to dryness in vacuo affording 1.66 g. of a brown glassy substance, which is used as is in the next step.

後処理

  1. additionA mixture of 2.1 g
  2. filtrationThe reaction mixture is filtered while hot, the solid material
  3. washwashed with ethanol
  4. extractionextracted with chloroform
  5. customevaporated to dryness in vacuo
  6. customaffording 1.66 g

出典と根拠

ORDレコード
ord-a98c89a3bfa24d5f82668d0f52283d80
出典データセット
uspto-grants-1979_11
特許番号
US04174400

反応ノート

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