Hydrogen Bromide → 2-Bromo-6-nitro-1-indanone

HRID 46627ノート

反応式

HRID 46627 の反応式
[N+:1]([C:4]1[CH:12]=[C:11]2[C:7]([CH2:8][CH2:9][C:10]2=[O:13])=[CH:6][CH:5]=1)([O-:3])=[O:2].[BrH:14].BrBr>C(O)(=O)C>[Br:14][CH:9]1[CH2:8][C:7]2[C:11](=[CH:12][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=2)[C:10]1=[O:13]

参加物

5

反応物 3

HCID 260Hydrogen BromideHCID 24408BromineHCID 905626-Nitroindan-1-one

生成物 1

HCID 110650202-Bromo-6-nitro-1-indanone

試薬・触媒・溶媒 1

HCID 176Acetic Acid溶媒2 回

実験手順

Analogously to Example 1 (a), reaction of 12.39 g (70.0 mmoles) of 6-nitro-1-indanone in 130 ml of glacial acetic acid, containing 0.5 ml of 48% strength aqueous hydrobromic acid, and 11.2 g (70 mmoles) of bromine in 70 ml of glacial acetic acid, in accordance with the instructions indicated above, gives 2-bromo-6-nitro-1-indanone of melting point 102°-105° C. which, as the pure product after reprecipitation from ethanol/water, has a melting point of 114°-116° C.

出典と根拠

ORDレコード
ord-95a2c99cc31542a6880abc096cfac5b9
出典データセット
uspto-grants-1979_11
特許番号
US04174397

反応ノート

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