2-Aminobiphenyl → 2-(o-Biphenylyl)thiophene

HRID 46642

反応式

HRID 46642 の反応式
N[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[S:14]1[CH:18]=[CH:17][CH:16]=[CH:15]1.N(OCCCC)=O>>[C:3]1([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=1[C:15]1[S:14][CH:18]=[CH:17][CH:16]=1

参加物

4

反応物 3

HCID 70152-AminobiphenylHCID 8030Thiophene2 回HCID 10996Butyl nitrite

生成物 1

HCID 142439862-(o-Biphenylyl)thiophene収率 34.8%

実験手順

In a 4-l Erlenmeyer flask were placed 100 g (0.600 mole) of Pfalz and Bauer o-aminobiphenyl, m.p. 49°-51° C., 3000 ml (38.2 moles) of thiophene and 90 ml (0.80 mole) of n-butyl nitrite. The mixture was thoroughly stirred and then allowed to stand at room temperature for eight days. Unreacted thiophene was removed by distillation. The residue was distilled at reduced pressure to give 49.4 g (34.8%) of 2-(o-biphenylyl)thiophene b.p. 138°-155° C. (0.1 mm), ND20 1.6465.

後処理

  1. customwas removed by distillation
  2. distillationThe residue was distilled at reduced pressure

出典と根拠

ORDレコード
ord-eccd3d4c1897434e80a4312eac06faaf
出典データセット
uspto-grants-1979_11
特許番号
US04174405

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