Pyrrolidine → t-Butyl 3-[4-(dimethylamino)-2-butynyl]-2-oxo-1-imidazolidinecarboxylate

反応式

N1CC[CH2:3][CH2:2]1.[C:6]([O:10][C:11]([N:13]1[CH2:17][CH2:16][NH:15][C:14]1=[O:18])=[O:12])([CH3:9])([CH3:8])[CH3:7].[CH3:19][N:20]1[CH2:24][CH2:23]N[C:21]1=O>>[CH3:19][N:20]([CH3:21])[CH2:24][C:23]#[C:2][CH2:3][N:15]1[CH2:16][CH2:17][N:13]([C:11]([O:10][C:6]([CH3:9])([CH3:7])[CH3:8])=[O:12])[C:14]1=[O:18]

参加物

反応物 3

HCID 31268Pyrrolidine

HCID 5676001-Methylimidazolidin-2-one

HCID 22008758Tert-butyl 2-oxoimidazolidine-1-carboxylate

生成物 1

HCID 19753288t-Butyl 3-[4-(dimethylamino)-2-butynyl]-2-oxo-1-imidazolidinecarboxylate

実験手順

This product, a liquid, was prepared according to Example 1 by substituting dimethylamine for pyrrolidine and 1-t-butoxycarbonyl-2-imidazolidinone for 1-methyl-2-imidazolidinone.

後処理

customThis product, a liquid, was prepared

出典と根拠

ORDレコード: ord-95bba8aa1f154b7bb360250663be4682
出典データセット: uspto-grants-1992_10
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US05157124

反応ノート

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