2-Naphthoyl chloride → HCID 10083909、化合物
反応式
[CH3:1][NH:2][C:3](=[S:6])[NH:4][NH2:5].[CH:7]1[C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH:10]=[CH:9][C:8]=1[C:17](Cl)=[O:18]>N1C=CC=CC=1>[CH3:1][NH:2][C:3](=[S:6])[NH:4][NH:5][C:17]([C:8]1[CH:9]=[CH:10][C:11]2[C:16](=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:7]=1)=[O:18]参加物
4
実験手順
To a stirred room temperature solution of 4-methylthiosemicarbazide (5.91 g, 5.62×10-2 mole) and pyridine (150 ml) was added 2-naphthoyl chloride (10.7 g, 5.61×10-2 mole). After stirring overnight, the pyridine was evaporated at reduced pressure. The concentrate was treated with water and the undissolved product was collected by filtration and dried by suction. Crystallization from acetone/ethanol afforded off-white needles, Mp 211° C. (decomp).
後処理
- customthe pyridine was evaporated at reduced pressure
- additionThe concentrate was treated with water
- filtrationthe undissolved product was collected by filtration
- customdried by suction
- customCrystallization from acetone/ethanol afforded off-white needles, Mp 211° C. (decomp)
出典と根拠
- ORDレコード
- ord-9e104bbd9b1346da800d02dfddfd02d3
- 出典データセット
- uspto-grants-1992_10
- 特許番号
- US05158968
反応ノート
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