Methyl isothiocyanate → 1-Benzoyl-4-methyl-3-thiosemicarbazide
反応式
[C:1]([NH:9][NH2:10])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:11][N:12]=[C:13]=[S:14]>C1COCC1>[C:1]([NH:9][NH:10][C:13]([NH:12][CH3:11])=[S:14])(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
4
実験手順
To a stirred solution of benzoic acid hydrazide (2.35 g, 1.73×10-2 mole) and THF (50 ml) was added a solution of methyl isothiocyanate (1.14 g, 1.56×10-2 mole) and THF (50 ml). The reaction was then refluxed for 2 hours before being cooled. The precipitate was collected by filtration and crystallized from ethanol, affording a colorless solid, Mp 199°-200° C.
後処理
- temperatureThe reaction was then refluxed for 2 hours
- temperaturebefore being cooled
- filtrationThe precipitate was collected by filtration
- customcrystallized from ethanol
- customaffording a colorless solid, Mp 199°-200° C.
出典と根拠
- ORDレコード
- ord-f2c3b89cbb2747b8a5b9f18973780669
- 出典データセット
- uspto-grants-1992_10
- 特許番号
- US05158968
反応ノート
読み込み中…