Potassium Carbonate → HCID 12411034、化合物

HRID 46775

反応式

HRID 46775 の反応式
[CH2:1]([NH:9][CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([O:20][CH3:21])[CH:13]=1)[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.C(=O)([O-])[O-].[K+].[K+].[CH2:28](I)[CH2:29][CH3:30]>CC(C)=O>[CH2:1]([N:9]([CH2:10][CH2:11][C:12]1[CH:17]=[CH:16][C:15]([O:18][CH3:19])=[C:14]([O:20][CH3:21])[CH:13]=1)[CH2:28][CH2:29][CH3:30])[CH2:2][C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 336431-IodopropaneHCID 215356AN-465/43411221

生成物 1

HCID 12411034HCID 12411034、化合物

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

A solution of 8 g of N-phenethyl-3,4-dimethoxyphenethylamine, 8 g of anhydrous potassium carbonate, 11 ml of propyl iodide and 80 ml of acetone was refluxed for 6 hours and the mixture was filtered. The filtrate was evaporated to dryness and the residue was taken up in 50 ml of water. The solution was extracted with methylene chloride and the organic extracts were washed with water, dried over magnesium sulfate, filtered and evaporated to dryness to obtain 9.37 g of raw N-phenethyl-N-propyl-3,4-dimethoxyphenethylamine in the form of an oil which was used as is for the next step.

後処理

  1. filtrationthe mixture was filtered
  2. customThe filtrate was evaporated to dryness
  3. extractionThe solution was extracted with methylene chloride
  4. washthe organic extracts were washed with water
  5. dry with materialdried over magnesium sulfate
  6. filtrationfiltered
  7. customevaporated to dryness

出典と根拠

ORDレコード
ord-35c268dcc23843a9bd9cbd95b479e615
出典データセット
uspto-grants-1979_11
特許番号
US04175136

関連ノート

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