Thionyl Chloride → 4-Cyano-3-fluorobenzoyl chloride

HRID 469341ノート

反応式

HRID 469341 の反応式
[C:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7](O)=[O:8])=[CH:5][C:4]=1[F:12])#[N:2].S(Cl)([Cl:15])=O>>[C:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7]([Cl:15])=[O:8])=[CH:5][C:4]=1[F:12])#[N:2]

参加物

3

反応物 2

HCID 24386Thionyl ChlorideHCID 27784684-Cyano-3-fluorobenzoic acid

生成物 1

HCID 199567394-Cyano-3-fluorobenzoyl chloride

実験手順

0.66 g (4.0 mmol) 4-cyano-3-fluoro-benzoic acid were mixed with 10 mL thionyl chloride and boiled for 2 h. The mixture was evaporated to dryness and coevaporated twice with toluene. The residue was reacted further as the crude product.

後処理

  1. customThe mixture was evaporated to dryness
  2. customThe residue was reacted further as the crude product

出典と根拠

ORDレコード
ord-5d904c35d39c4e24855c8b7d93a46084
出典データセット
uspto-grants-2014_01
特許番号
US08629137B2

反応ノート

読み込み中…