Thionyl Chloride → 3-Cyano-5-fluoro-benzoic acid chloride
反応式
[C:1]([C:3]1[CH:4]=[C:5]([CH:9]=[C:10]([F:12])[CH:11]=1)[C:6](O)=[O:7])#[N:2].S(Cl)([Cl:15])=O>>[C:1]([C:3]1[CH:4]=[C:5]([CH:9]=[C:10]([F:12])[CH:11]=1)[C:6]([Cl:15])=[O:7])#[N:2]参加物
3
実験手順
1.65 g (10.0 mmol) 3-cyano-5-fluorobenzoic acid were boiled for 2 h with 7.27 mL (100 mmol) thionyl chloride with stirring. The reaction mixture was evaporated to dryness i. vac. and coevaporated twice with toluene. The residue was reacted further as the crude product.
後処理
- customThe reaction mixture was evaporated to dryness i
- customThe residue was reacted further as the crude product
出典と根拠
- ORDレコード
- ord-283c3667309b4b41b7d6e7a741c75ffd
- 出典データセット
- uspto-grants-2014_01
- 特許番号
- US08629137B2
反応ノート
読み込み中…