Glyoxylic Acid → 4-Hydroxyphenylglycine
反応式
[C:1]([OH:5])(=[O:4])[CH:2]=O.C([O-])(=O)C.[NH4+:10].[C:11]1([OH:17])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>O>[CH:13]1[C:14]([CH:2]([NH2:10])[C:1]([OH:5])=[O:4])=[CH:15][CH:16]=[C:11]([OH:17])[CH:12]=1参加物
5
実験手順
30 g of an aqueous 40% glyoxylic acid solution are added to 70 ml of water, and 37.5 g of ammonium acetate and 22.5 g of phenol are added thereto under stirring. The mixture is stirred at room temperature for 41 hours. The crystalline precipitates are collected by filtration under cooling, and then successively washed with water and methanol. 7.8 g of DL-p-hydroxyphenylglycine are thereby obtained as white crystals. Yield: 28.9%, M.p. 225°-228° C. (decomp.).
後処理
- additionare added
- stirringThe mixture is stirred at room temperature for 41 hours
- customThe crystalline precipitates
- filtrationare collected by filtration
- temperatureunder cooling
- washsuccessively washed with water and methanol
出典と根拠
- ORDレコード
- ord-4a71fba6378949a183990fe45aff8c26
- 出典データセット
- uspto-grants-1979_11
- 特許番号
- US04175206
反応ノート
読み込み中…