Potassium ethylxanthate → HCID 178527769、化合物

HRID 469823

反応式

HRID 469823 の反応式
[NH2:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Br:8])[C:3]=1[OH:9].CCO[C:13]([S-])=[S:14].[K+]>CCO>[Br:8][C:4]1[C:3]2[O:9][C:13]([SH:14])=[N:1][C:2]=2[CH:7]=[CH:6][CH:5]=1

参加物

4

反応物 2

HCID 2735045Potassium ethylxanthateHCID 155315062-Amino-6-bromophenol

生成物 1

HCID 178527769HCID 178527769、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

5 g (26.6 mmol) 2-amino-6-bromo-phenol are dissolved in 20 ml EtOH and 6.52 g (39.9 mmol) potassium ethyl xanthogenate are added. This mixture is stirred for 6 h at reflux temperature. After cooling to room temperature, the reaction mixture is concentrated in vacuo and 50 ml water are added. With the addition of acetic acid, a pH of 5 is adjusted. The product starts to crystallize and is filtered off, washed 2× with water and dried to afford the title compound.

後処理

  1. temperatureat reflux temperature
  2. concentrationthe reaction mixture is concentrated in vacuo and 50 ml water
  3. additionare added
  4. additionWith the addition of acetic acid
  5. customto crystallize
  6. filtrationis filtered off
  7. washwashed 2× with water
  8. customdried

出典と根拠

ORDレコード
ord-663e6cbbc2c24d0084ee0ef8d1a887a7
出典データセット
uspto-grants-2014_01
特許番号
US08629168B2

関連ノート

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