Ethyl o-cyanomethylcinnamate → Ethyl o-(cyanomethyl)hydrocinnamate

HRID 46989

反応式

HRID 46989 の反応式
[C:1]([CH2:3][C:4]1[CH:16]=[CH:15][CH:14]=[CH:13][C:5]=1[CH:6]=[CH:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])#[N:2].[H][H]>C(O)C.[Pd]>[C:1]([CH2:3][C:4]1[CH:16]=[CH:15][CH:14]=[CH:13][C:5]=1[CH2:6][CH2:7][C:8]([O:10][CH2:11][CH3:12])=[O:9])#[N:2]

参加物

5

反応物 2

HCID 53697120Ethyl o-cyanomethylcinnamateHCID 178418361HCID 178418361、化合物

生成物 1

HCID 54486935Ethyl o-(cyanomethyl)hydrocinnamate

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 702Ethanol溶媒

実験手順

Ethyl o-(cyanomethyl)cinnamate (75.1 g., 0.35 mole) is dissolved in ethanol (300 ml.) and hydrogenated at a pressure of 1 atmosphere and room temperature over 2.5 g. of a 5% palladium on charcoal catalyst. When the theoretical amount of hydrogen (0.35 mole) has been absorbed, the catalyst is filtered off and the ethanol removed by distillation at reduced pressure to yield ethyl o-(cyanomethyl)hydrocinnamate.

後処理

  1. customhydrogenated at a pressure of 1 atmosphere and room temperature over 2.5 g
  2. filtrationthe catalyst is filtered off
  3. customthe ethanol removed by distillation at reduced pressure

出典と根拠

ORDレコード
ord-5a2238bf2cb243deb54f41fa66ed13b8
出典データセット
uspto-grants-1979_11
特許番号
US04175203

関連ノート

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