Hydrochloric Acid → 4,4-Dimethylcyclohexane-1-carbaldehyde

HRID 471800ノート

反応式

HRID 471800 の反応式
[CH3:1][C:2]1([CH3:11])[CH2:7][CH2:6][C:5](=[CH:8][O:9]C)[CH2:4][CH2:3]1.Cl>C1COCC1.C(OCC)C.[Cl-].[Na+].O.O>[CH3:1][C:2]1([CH3:11])[CH2:7][CH2:6][CH:5]([CH:8]=[O:9])[CH2:4][CH2:3]1

参加物

7

反応物 2

HCID 313Hydrochloric AcidHCID 589086674-Methoxymethylene-1,1-dimethyl-cyclohexane

生成物 1

HCID 222352954,4-Dimethylcyclohexane-1-carbaldehyde

試薬・触媒・溶媒 4

HCID 962Water溶媒HCID 3283Diethyl Ether溶媒HCID 8028Tetrahydrofuran溶媒HCID 57417360Sodium chloride; water溶媒

実験手順

A solution of (4,4-dimethyl cyclohexylidene)methyl methyl ether (6.7 g, 0.043 mol) in THF (200 mL) containing 6M HCl (aq) (60 mL) was stirred at room temperature for 24 hr. The reaction mixture was diluted with a mixture of ethyl ether, hexanes, brine and water. The mixture was separated and the aqueous phase was extracted with ethyl ether. The combined organic phase was washed with brine, dried over Na2SO4, and concentrated in vacuo, affording 4,4-dimethylcyclohexanecarbaldehyde as a yellow oil, used without further purification.

後処理

  1. customThe mixture was separated
  2. extractionthe aqueous phase was extracted with ethyl ether
  3. washThe combined organic phase was washed with brine
  4. dry with materialdried over Na2SO4
  5. concentrationconcentrated in vacuo

出典と根拠

ORDレコード
ord-f6b247f26da348388eb769d2020c78e2
出典データセット
uspto-grants-2014_01
特許番号
US08633175B2

反応ノート

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