関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | 2-(1-(tetrahydro-2H-pyran-2-yl)-1H-benzo[d]imidazol-5-yl)propan-2-amine | HCID 71272671 | — |
| 反応物 | HCID 178478345 | HCID 178478345 | — |
| 生成物 | HCID 178456847 | HCID 178456847 | — |
反応手順
A neat mixture of 94 (691 mg, 2.67 mmol) and 53 (210 mg, 0.89 mmol) was stirred under nitrogen at 140° C. for 18 h. The dark brown mixture was cooled to RT and was purified by preparative HPLC to afford 25 mg (7.5%) of I-17 as white solid.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US08637537B2 |
|---|
| 出典データセット | uspto-grants-2014_01 |
|---|
| ORD ID | ord-e4d49a00a1074bd1aacd2d18c6ee466c |
|---|
| 出典メモ | uspto-grants-2014_01 |
|---|
