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1-(4-Fluorophenyl)cyclobutanecarboxylic acid → (R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclobutanecarboxamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(4-Fluorophenyl)cyclobutanecarboxylic acid | HCID 16769017 | — |
| 反応物 | propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate | HCID 86655417 | — |
| 生成物 | (R)-2-(7-(1-(4-fluorophenyl)-N-methylcyclobutanecarboxamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid | HCID 53248760 | — |
反応手順
The title compound was prepared using analogous procedures described in Example 1 (Method A) from 1-(4-fluorophenyl)cyclobutanecarboxylic acid and propyl [(7R)-7-(methylamino)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]acetate. MS (+ESI) m/z: 435.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08637671B2 |
| 出典データセット | uspto-grants-2014_01 |
| ORD ID | ord-a0728bbecc164894ab0dc63ee6fc5013 |
| 出典メモ | uspto-grants-2014_01 |