Methyl iodide → HCID 19838283、化合物
反応式
[OH:1][C:2]1[C:3]([CH2:15][CH2:16][CH3:17])=[C:4]([CH:7]=[C:8]([N+:12]([O-:14])=[O:13])[C:9]=1[O:10][CH3:11])[CH:5]=[O:6].[C:18](=O)([O-])[O-].[K+].[K+].CI>CN(C)C=O>[CH3:18][O:1][C:2]1[C:3]([CH2:15][CH2:16][CH3:17])=[C:4]([CH:7]=[C:8]([N+:12]([O-:14])=[O:13])[C:9]=1[O:10][CH3:11])[CH:5]=[O:6]参加物
5
実験手順
A solution of the product from step (c) (40.2 g), potassium carbonate (46.5 g) and methyl iodide (20.9 ml) in dry dimethylformamide (150 ml) was stirred at 20° C. for 16 hours. The solvent was evaporated and the residue quenched with water. The aqueous phase was extracted with ethyl acetate which was washed with brine, dried, filtered and evaporated to leave a yellow oil (27.4 g), MS; m/e 283.
後処理
- customThe solvent was evaporated
- customthe residue quenched with water
- extractionThe aqueous phase was extracted with ethyl acetate which
- washwas washed with brine
- customdried
- filtrationfiltered
- customevaporated
出典と根拠
- ORDレコード
- ord-1afefe034b8c4d60902ea14a6bd72dd9
- 出典データセット
- uspto-grants-1989_12
- 特許番号
- US04885313
反応ノート
読み込み中…