反応式
C(O)(=O)C[CH2:3][CH2:4][CH2:5][C:6]([OH:8])=[O:7].C[O:12][C:13]([O:16][CH3:17])([CH3:15])C.[CH3:18]O>>[CH3:17][O:16][C:13](=[O:12])[CH2:15][CH2:3][CH2:4][CH2:5][C:6]([O:8][CH3:18])=[O:7]参加物
4
実験手順
According to a process described in J. Org. Chem. 24, 261 (1959), methyl esters of carboxylic acid are obtained by the reaction of carboxylic acids with methanol in the presence of acetone dimethyl acetal, the dimethyl acetal acting as a hydrophilic agent and supplier of methanol. If adipic acid, methanol and acetone dimethyl acetal are reacted in a molar ratio of 4:5:8, a 94% yield of dimethyladipate is obtained. The economy of this procedure is impaired by the fact that the use of acetone dimethyl acetal increases the raw material costs, and the formation of acetone during the course of the reaction increases the amount of distillation required.
出典と根拠
- ORDレコード
- ord-025bc338f62c40279541933583551318
- 出典データセット
- uspto-grants-1989_12
- 特許番号
- US04885383
関連ノート
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