Sodium Hydroxide → disodium 2-[[N-(chloroacetyl)glycyl]amino]malonate

HRID 477203ノート

反応式

HRID 477203 の反応式
[Cl:1][CH2:2][C:3]([NH:5][CH2:6][C:7]([NH:9][CH:10]([C:16]([O:18]CC)=[O:17])[C:11]([O:13]CC)=[O:12])=[O:8])=[O:4].[OH-].[Na+:22]>>[Cl:1][CH2:2][C:3]([NH:5][CH2:6][C:7]([NH:9][CH:10]([C:16]([O-:18])=[O:17])[C:11]([O-:13])=[O:12])=[O:8])=[O:4].[Na+:22].[Na+:22]

参加物

3

反応物 2

HCID 14798Sodium HydroxideHCID 15053734Diethyl 2-[[N-(chloroacetyl)glycyl]amino]malonate

生成物 1

HCID 19837444disodium 2-[[N-(chloroacetyl)glycyl]amino]malonate

実験手順

Diethyl 2-[[N-(chloroacetyl)glycyl]amino]malonate (0.68 g) is added to 1N aqueous sodium hydroxide (4.7 ml), and the mixture is reacted at room temperature for 10 hours, and the reaction mixture is concentrated. The residue is washed with methanol to give disodium 2-[[N-(chloroacetyl)glycyl]amino]malonate (0.65 g).

後処理

  1. customthe mixture is reacted at room temperature for 10 hours
  2. concentrationthe reaction mixture is concentrated
  3. washThe residue is washed with methanol

出典と根拠

ORDレコード
ord-952031986fac4984b79482a3558ef6ef
出典データセット
uspto-grants-1989_12
特許番号
US04886894

反応ノート

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