Epichlorohydrin → 4-Glycidoxy-2-nitroacetanilide
反応式
[CH2:1]([CH:3]1[O:5][CH2:4]1)Cl.[N+:6]([C:9]1[CH:10]=[C:11]([OH:19])[CH:12]=[CH:13][C:14]=1[NH:15][C:16](=[O:18])[CH3:17])([O-:8])=[O:7]>[OH-].[Na+]>[N+:6]([C:9]1[CH:10]=[C:11]([CH:12]=[CH:13][C:14]=1[NH:15][C:16](=[O:18])[CH3:17])[O:19][CH2:1][CH:3]1[O:5][CH2:4]1)([O-:8])=[O:7]参加物
4
実験手順
150 ml of epichlorohydrin are added, at ambient temperature, to a solution of 0.376 mol (73.7 g) of 3-nitro-4-acetylaminophenol in 375 ml of 1.1N sodium hydroxide solution. The reaction medium is left to stand at ambient temperature for 48 hours, with thorough stirring, and the expected product which has precipitated is then filtered off. After drying in vacuo and recrystallisation from benzene, this product melts at 123° C.
後処理
- waitThe reaction medium is left
- customthe expected product which has precipitated
- filtrationis then filtered off
- dry with materialAfter drying in vacuo and recrystallisation from benzene
出典と根拠
- ORDレコード
- ord-6d1a094025774fb68477135b6ab6ba48
- 出典データセット
- uspto-grants-1989_12
- 特許番号
- US04888025
反応ノート
読み込み中…