Hydrochloric Acid → HCID 178518561、化合物

HRID 477750

反応式

HRID 477750 の反応式
C([O:3][C:4]([N:6]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[NH:7][C:8]([NH2:10])=[S:9])=O)C.[OH-].[Na+].Cl>O>[OH:3][C:4]1[N:6]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[N:7]=[C:8]([SH:9])[N:10]=1

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 857731911-Ethoxycarbonyl-1-phenythiosemicarbazide

生成物 1

HCID 178518561HCID 178518561、化合物収率 86.6%

試薬・触媒・溶媒 1

HCID 962Water溶媒

反応条件

温度
25 °C

実験手順

The product of stage (a) (28.9 g) was treated with a solution of sodium hydroxide (7.5 g) in water (150 ml). The suspension was heated under reflux with stirring for 45 minutes and then cooled to 25° C. The pH of the solution was adjusted to 1.0 with concentrated hydrochloric acid and the resulting solid was filtered and washed with water to give 20.2 g of the desired product.

後処理

  1. temperatureThe suspension was heated
  2. temperatureunder reflux
  3. filtrationthe resulting solid was filtered
  4. washwashed with water

出典と根拠

ORDレコード
ord-d83609b28ff9451b83aa088a0179c252
出典データセット
uspto-grants-1989_12
特許番号
US04889553

関連ノート

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