Water → HCID 338434、化合物
反応式
[CH3:1][C:2]1[C:3]([CH2:13]O)=[N:4][N:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:6]=1.S(Cl)([Cl:17])=O.O.C(=O)([O-])[O-].[K+].[K+]>ClCCl>[Cl:17][CH2:13][C:3]1[C:2]([CH3:1])=[N:6][N:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[N:4]=1参加物
6
実験手順
5.0 g of (5-methyl-2-phenyl-1,2,3-triazol4-yl)methan-1-ol was dissolved in 35 ml of dichloromethane, then 6.3 g of thionyl chloride was added dropwise thereto under cooling with ice. After stirring for 1 hour at room temperature, 100 ml of water was added. The resulting solution was made alkaline with 8 g of potassium carbonate, then extracted with chloroform. The organic phase was washed with water and a saturated salt solution, then dried over anhydrous sodium sulfate. After the solvent was distilled off, 5.2 g of the aimed compound was obtained.
後処理
- temperatureunder cooling with ice
- extractionextracted with chloroform
- washThe organic phase was washed with water
- dry with materiala saturated salt solution, then dried over anhydrous sodium sulfate
- distillationAfter the solvent was distilled off
出典と根拠
- ORDレコード
- ord-731a40a655e04c39ad33a8669a41bb40
- 出典データセット
- uspto-grants-2003_11
- 特許番号
- US06642234B1
反応ノート
読み込み中…