Sodium bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate → bicyclo2.2.1heptane-2,3-dicarboxylic acid, disodium salt

HRID 478879

反応式

HRID 478879 の反応式
[CH:1]12[CH2:7][CH:4]([CH:5]=[CH:6]1)[CH:3]([C:8]([O-:10])=[O:9])[CH:2]2[C:11]([O-:13])=[O:12].[Na+:14].[Na+]>O.[Pd]>[CH:1]12[CH2:7][CH:4]([CH2:5][CH2:6]1)[CH:3]([C:8]([O-:10])=[O:9])[CH:2]2[C:11]([O-:13])=[O:12].[Na+:14].[Na+:14]

参加物

4

反応物 1

HCID 21908873Sodium bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate

生成物 1

HCID 21981355bicyclo2.2.1heptane-2,3-dicarboxylic acid, disodium salt

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 962Water溶媒

実験手順

To a solution of disodium bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylate (10.0 g) in water (100 g) was added 0.5 g palladium on activated carbon (5 wt%). The mixture was transferred into a Parr reactor and was subjected to hydrogenation (50 psi, room temperature) for 8 hours. The activated carbon was filtered out, and the water was removed in vacuo at 75° C. The resulting product (m.p >300° C.) was dried and milled. NMR and IR analyses were consistent with that of the expected structure.

後処理

  1. filtrationThe activated carbon was filtered out
  2. customthe water was removed in vacuo at 75° C
  3. customThe resulting product (m.p >300° C.) was dried
  4. custommilled

出典と根拠

ORDレコード
ord-8d7469250ebd4d85a80499fcf856614c
出典データセット
uspto-grants-2003_11
特許番号
US06642290B1

関連ノート

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