Hydrazine hydrate (1:1) → 6-Hydrazino-5-nitroso-pyrimidine-2,4-diamine

HRID 479095ノート

反応式

HRID 479095 の反応式
O.[NH2:2][NH2:3].CS[C:6]1[N:11]=[C:10]([NH2:12])[N:9]=[C:8]([NH2:13])[C:7]=1[N:14]=[O:15]>CN(C=O)C>[NH:2]([C:6]1[N:11]=[C:10]([NH2:12])[N:9]=[C:8]([NH2:13])[C:7]=1[N:14]=[O:15])[NH2:3]

参加物

4

反応物 2

HCID 24654Hydrazine hydrate (1:1)HCID 180033426-(Methylsulfanyl)-5-nitrosopyrimidine-2,4-diamine

生成物 1

HCID 112522426-Hydrazino-5-nitroso-pyrimidine-2,4-diamine

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

Hydrazine hydrate (55% solution, 14.5 mL) was added rapidly to a suspension of (12.0 g; 64.9 mmol) of 6-Methylthio-5-nitroso-pyrimidine-2,4-diamine 2 in DMF at room temperature. The mixture was allowed to stir overnight and then the bright pink mixture was filtered and the solid washed several times with DMF followed by ether and then air dried to give 9.53 g of 6-Hydrazino-5-nitroso-pyrimidine-2,4-diamine as bright pink solid.

後処理

  1. filtrationthe bright pink mixture was filtered
  2. washthe solid washed several times with DMF
  3. customair dried

出典と根拠

ORDレコード
ord-e1e2e8955e9c4de5a6a204fa82d2df30
出典データセット
uspto-grants-2003_11
特許番号
US06642381B2

反応ノート

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