4-Chloroaniline → (E)-styryl-N-4-chlorophenyl Sulfonamide

反応式

[CH:1](/[S:9](Cl)(=[O:11])=[O:10])=[CH:2]\[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[Cl:13][C:14]1[CH:20]=[CH:19][C:17]([NH2:18])=[CH:16][CH:15]=1>>[CH:1](/[S:9]([NH:18][C:17]1[CH:19]=[CH:20][C:14]([Cl:13])=[CH:15][CH:16]=1)(=[O:11])=[O:10])=[CH:2]\[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

参加物

反応物 2

HCID 78124-Chloroaniline

HCID 5369377(E)-2-phenylethene-1-sulfonyl chloride

生成物 1

HCID 8497751(E)-styryl-N-4-chlorophenyl Sulfonamide収率 56%

実験手順

A solution of (E)-styrylsulfonyl chloride (10 mmol) and 4-chloroaniline (10 mmol) was subjected to General Procedure 1, part B. The title compound, melting point 107-109° C. was obtained in 56% yield.

出典と根拠

ORDレコード: ord-4d97edb1a41243d3902ee458ef565d4e
出典データセット: uspto-grants-2003_11
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06646009B2

反応ノート

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