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2-(4-Aminomethylphenyl)-4-phenyl-5-(4-pyridyl)-imidazole → 2-(4-Biotinamidomethylphenyl)-1-methyl-4-phenyl-5-(4-pyridyl)-imidazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(4-Aminomethylphenyl)-4-phenyl-5-(4-pyridyl)-imidazole | HCID 18771539 | — |
| 反応物 | n-Hydroxysuccinimide biotin | HCID 86743017 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 2-(4-Biotinamidomethylphenyl)-1-methyl-4-phenyl-5-(4-pyridyl)-imidazole | HCID 131720117 | — |
反応手順
To a solution containing 2-(4-Aminomethylphenyl)-4-phenyl-5-(4-pyridyl)-imidazole (1 equivalent) in DMF was added N-hydroxysuccinimide biotin (1.2 eq). Follwing normal workup and chromatography the title compound was obtained: CIMS (NH3, m/z): 523 (M++H).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06645989B2 |
| 出典データセット | uspto-grants-2003_11 |
| ORD ID | ord-f338e18b179a493db67ab99d6cbda2f9 |
| 出典メモ | uspto-grants-2003_11 |