5-Amino-2-naphthol → 8-(4-Methylpiperazin-1-yl)naphthalen-3-ol
反応式
[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([C:8]2[CH:9]=[C:10](O)[CH:11]=[CH:12][CH:13]=2)[CH2:4][CH2:3]1.NC1C=CC=[C:20]2C=1C=[CH:23][C:22]([OH:26])=[CH:21]2.C(=O)([O-])[O-].[Na+].[Na+]>C(O)CCC>[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([C:8]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:9]=2[CH:20]=[CH:21][C:22]([OH:26])=[CH:23]3)[CH2:4][CH2:3]1参加物
5
実験手順
Compound 53A is prepared according to the same procedure as that for 13A, using the following reactants: 8-aminonaphthalen-3-ol (10 g, 62.8 mmol), 2-chloro-N-(2-chlorethyl)-N-methylethananine hydrochloride (11.8 g, 62.8 mmol), sodium carbonate (3.32 g, 31.4 mmol), 1-butanol (200 ml).
出典と根拠
- ORDレコード
- ord-1bdb645bbb454864b021f0025d4551f1
- 出典データセット
- uspto-grants-1998_08
- 特許番号
- US05789412
反応ノート
読み込み中…