Chlorosulfonic acid → 6-(Chlorosulfonyl)-1,7,8,9-tetrahydro-8-methyl-2H-pyrrolo[3,4-f]quinoxaline-2,3(4H)-dione
反応式
[CH3:1][N:2]1[CH2:14][C:13]2[CH:12]=[CH:11][C:10]3[NH:9][C:8](=[O:15])[C:7](=[O:16])[NH:6][C:5]=3[C:4]=2[CH2:3]1.[Cl:17][S:18](O)(=[O:20])=[O:19]>>[Cl:17][S:18]([C:12]1[C:13]2[CH2:14][N:2]([CH3:1])[CH2:3][C:4]=2[C:5]2[NH:6][C:7](=[O:16])[C:8](=[O:15])[NH:9][C:10]=2[CH:11]=1)(=[O:20])=[O:19]参加物
3
実験手順
A solution of 1,7,8,9-tetrahydro-8-methyl-2H-pyrrolo[3,4-f]quinoxaline-2,3(4H)-dione in chlorosulfonic acid was stirred at 120° C. for 3 hours, whereafter it was cooled and poured on ice. This afforded a crystalline precipitate of the product, which was filtered off and washed with water, mp>300° C.
後処理
- temperaturewas cooled
- additionpoured on ice
- customThis afforded a crystalline precipitate of the product, which
- filtrationwas filtered off
- washwashed with water, mp>300° C.
出典と根拠
- ORDレコード
- ord-17ac3bacb25a4d7096ab42d16b38ea72
- 出典データセット
- uspto-grants-2004_03
- 特許番号
- US06703391B2
反応ノート
読み込み中…