Water → 4-Chloroisatoic anhydride

HRID 482310ノート

反応式

HRID 482310 の反応式
[OH2:1].[C:2]1(C)C=CC=CC=1.[Cl:9][C:10]1[CH:11]=[C:12]([NH2:19])[C:13](=[CH:17][CH:18]=1)[C:14]([OH:16])=[O:15]>O1CCCC1>[CH:18]1[C:10]([Cl:9])=[CH:11][C:12]2[NH:19][C:2]([O:15][C:14](=[O:16])[C:13]=2[CH:17]=1)=[O:1]

参加物

5

反応物 3

HCID 962Water2 回HCID 1140TolueneHCID 666462-Amino-4-chlorobenzoic acid

生成物 1

HCID 3291054-Chloroisatoic anhydride収率 93%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

According to the same manner as in Example 5, except that 171.6 g of water and 171.6 g of toluene were used in place of 78.9 g of water and 315.5 g of tetrahydrofuran, and that 4-chloroanthranilic acid was used in place of 4,5-dimethoxyanthranilic acid, 80.9 g of 7 -chloroisatoic anhydride (purity: 91 %) was obtained.

出典と根拠

ORDレコード
ord-a15ab25236704ed1acf9698969699689
出典データセット
uspto-grants-1998_08
特許番号
US05795984

反応ノート

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