Acetonitrile → 2-(2-Pentynyl)-2-cyclopenten-1-one

HRID 482786ノート

反応式

HRID 482786 の反応式
[CH2:1]([C:6]1(C(OCC=C)=O)[CH2:10][CH2:9][CH2:8][C:7]1=[O:11])[C:2]#[C:3][CH2:4][CH3:5].C(#N)C>C([O-])(=O)C.[Pd+2].C([O-])(=O)C>[CH2:1]([C:6]1[C:7](=[O:11])[CH2:8][CH2:9][CH:10]=1)[C:2]#[C:3][CH2:4][CH3:5]

参加物

4

反応物 2

HCID 6342AcetonitrileHCID 10868228Cyclopentanecarboxylic acid, 2-oxo-1-(2-pentynyl)-, 2-propenyl ester

生成物 1

HCID 110080722-(2-Pentynyl)-2-cyclopenten-1-one収率 85%

試薬・触媒・溶媒 1

HCID 167845palladium(II) acetate触媒

実験手順

A vessel was charged with 1 mole of allyl 1-(2-pentynyl)-2-oxocyclopentanecarboxylate of the following formula ##STR5## 20 moles of acetonitrile and 0.01 mole of palladium acetate. At room temperature, they were rapidly stirred. The mixture was then heated to the boiling point of the solvent, and the reaction was carried out under reflux for 30 minutes. After the reaction, the reaction mixture was distilled under reduced pressure in a customary manner to give 2-(2-pentynyl)-2-cyclopenten-1-one (PCP for short) in a yield of 85%. This compound was identified by using its IR, NMR and mass spectra.

後処理

  1. temperatureThe mixture was then heated to the boiling point of the solvent
  2. temperatureunder reflux for 30 minutes
  3. customAfter the reaction
  4. distillationthe reaction mixture was distilled under reduced pressure in a customary manner

出典と根拠

ORDレコード
ord-37b3470a4d4f47938b25d97c9d4d8c96
出典データセット
uspto-grants-1986_03
特許番号
US04575570

反応ノート

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