Hydrochloric Acid → 2-fluoro-3-methylpentanoic acid

HRID 483310ノート

反応式

HRID 483310 の反応式
[F:1][CH:2]([CH:8]([CH3:11])[CH2:9][CH3:10])[C:3]([O:5]CC)=[O:4].[OH-].[Na+].Cl>>[F:1][CH:2]([CH:8]([CH3:11])[CH2:9][CH3:10])[C:3]([OH:5])=[O:4]

参加物

4

反応物 3

HCID 313Hydrochloric AcidHCID 14798Sodium HydroxideHCID 19752044Ethyl 2-fluoro-3-methylpentanoate

生成物 1

HCID 2568962-fluoro-3-methylpentanoic acid

実験手順

To 8.5 g of the compound (iv) was added 1N NaOH aqueous solution, followed by stirring at room temperature for 8 hours. The solution was acidified with dilute hydrochloric acid and then extracted with ether. The extract was freed of ether by distillation. Thus there was obtained 2-fluoro-3-methylpentanoic acid (v).

後処理

  1. extractionextracted with ether
  2. distillationThe extract was freed of ether by distillation

出典と根拠

ORDレコード
ord-3ee9725470c043b7b30ecdb68591553f
出典データセット
uspto-grants-1993_07
特許番号
US05225105

反応ノート

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