Acrylic Acid → Oxan-2-yl prop-2-enoate

HRID 483327

反応式

HRID 483327 の反応式
[C:1]([OH:5])(=[O:4])[CH:2]=[CH2:3].[O:6]1[CH:11]=[CH:10][CH2:9][CH2:8][CH2:7]1>ClCCl>[C:1]([O:5][CH:7]1[CH2:8][CH2:9][CH2:10][CH2:11][O:6]1)(=[O:4])[CH:2]=[CH2:3]

参加物

4

反応物 2

HCID 6581Acrylic AcidHCID 80803,4-dihydro-2H-pyran

生成物 1

HCID 21909470Oxan-2-yl prop-2-enoate収率 26%

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A solution of 10.5 g (146 mmol, 10 ml) acrylic acid and 14.0 g (166 mmol, 15.2 ml) dihydropyran in 40 ml dichloromethane was stirred at room temperature for one day. The mixture was washed with saturated aqueous sodium bicarbonate and the organic layer was concentrated in vacuo. The residue was distilled to give 5.93 g (38.0 mmol, 26% yield) tetrahydropyran-2-yl acrylate, bp 40° C. at 0.2 torr.

後処理

  1. washThe mixture was washed with saturated aqueous sodium bicarbonate
  2. concentrationthe organic layer was concentrated in vacuo
  3. distillationThe residue was distilled

出典と根拠

ORDレコード
ord-af2beb6a145648deba41da0b6adb48c0
出典データセット
uspto-grants-1993_07
特許番号
US05225316

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